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It also demonstrates that nitrocatechol derivatives of chalcone may function as COMT and MAO-B inhibitors [167]

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However, due to the unpleasant odor of selenols and aliphatic selenides, and also its toxicity the selenium chemistry faced a serious setback

ROS also enhance their proliferation via two mechanisms: either by damaging biological molecules, leading to gene mutation and inflammation, or through abnormal oxidative stress redox signaling, which distorts signaling pathways and drives cancer progression