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And if left unchecked can eventually lead to neurodegenerative diseases such as Alzheimers disease, Parkinsons disease, and dementia
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The impact of metabolic activity on ER homeostasis is most evident from the association of ER stress with obesityparticularly in highly metabolically active tissues such as the liver, pancreas, and adipose (Cnop et al., 2012)
doi: 10.3390/ijms222413384 32 CaoSSKaufmanRJ
