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Summary: Vitamin B12 Toxicity Can too much vitamin B12 kill you

We posited that LLII MOTS-c treatment would cause metabolic reprogramming in old mice
Consistent with the observations in human elderly Leydig cells, H2O2-induced senescent TM3 Leydig cells exhibited a predominant nuclear localization of FOXO4, in contrast to untreated controls where it remained mostly cytoplasmic

For those unfamiliar with why this happens, the discomfort can feel alarming and lead to premature discontinuation of an otherwise well-designed protocol
