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PadyukovLSeielstadMOngRTDingBRonnelidJSeddighzadehMet al

A common strategy in the treatment of cystic fibrosis, in which dehydrated mucus results from a genetic defect in the cystic fibrosis transmembrane conductance regulator gene, is to inhale hypertonic salt aerosols 88 , which draw water by osmosis from the airway epithelium, lifting mucus off compressed cilia and enabling it to move freely and function effectively

While they appear to be protruding through the diaphragm and extending into the thoracic cavity, they actually are attached to and covered by a thin fibrous portion of the diaphragm (Eustis et al