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Although the tumors that develop in these mice demonstrate translocations, amplifications, and deletions, the translocated regions are not recognizably syntenic with known human translocations suggesting that these sarcomas more closely reflect adult sarcomas

It was found that PLC-1 could hydrolyze PI(4,5)P2 to produce IP3 and DAG, which targeted to reduce the level of PI(4,5)P2 in plasma membrane, which made PI(4,5)P2 binding protein cofilin released into cytoplasm from its inactive membrane association state, thereby increasing actin in breast cancer cells to promote cell migration activity

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A Mann-Whitney test was used to compare the AUCs between dietary groups