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COA per lot available Packaging: Sealed vials suitable for standard laboratory handling Storage & Stability Store lyophilized vials in a cool, dry place, protected from light and moisture

The mammalian sirtuins (Sirt1--Sirt7) participate in a number of cellular and physiological functions such as gene silencing, apoptosis, mitochondrial function, energy homeostasis, and longevity [237].Transgenic mice with overexpression of the sirt1 gene demonstrate decreased lipid-induced inflammation, improved glucose tolerance, and protection from hepatic steatosis when fed a high-fat diet [238]

Future studies will be focused on optimizing the MQ-scaffold lead series to generate more potent NNMT inhibitors with significantly improved drug-like ADME profile

More serious side effects are rare but can occur
