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Coskun PE, Wyrembak J, Derbereva O, Melkonian G, Doran E, Lott IT, Head E, Cotman CW, Wallace DC
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NLRP3 specifically interacts with NEK7, and after the activation of the inflammasome, the NEK7-NLRP3 interaction increases, leading to the oligomerization of NEK7 with NLRP3 into a complex
As expected, in this knockout strain, we see no GUS activity in cultured cells (Fig
