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During this process, acetyl-CoA produced by the pyruvate dehydrogenase (PDC) complex in muscle exceeds the processing capacity of the tricarboxylic acid (TCA) cycle

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KDIGO (2024) clinical practice guideline for the evaluation and management of chronic kidney disease

Specifically, lysine undergoes hydroxylation to form intermediate compounds, which are further transformed into L-carnitine under the catalysis of enzymes
