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When making referral decisions, your doctor may use the weighted 7-point checklist which has been recommended by NICE (National Institute for Health and Care Excellence) for routine use in UK general practice, as follows: All suspicious pigmented skin lesions that score 3 points or more using this check list should be referred urgently (within 2 weeks) to a dermatologist for professional clinical assessment

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Studies have shown that the lutein levels in the blood plasma increase during pregnancy, although the reasons for this are not yet known