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It also inhibits the expression of phosphoenolpyruvate carboxykinase (PEPCK) and glucose-6-phosphatase (G6Pase), key enzymes in gluconeogenesis (Hardie et al

[DOI] [PMC free article] [PubMed] [Google Scholar] 203.Shinohara Y., Saito I., Kobayashi S., Uchiyama S

In addition to inducing apoptosis in AML cells, CB-839 inhibits also the mTOR signaling pathway [54]

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