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Interestingly, we have 2 different types of Melanin pigments

All-trans retinoic acid induces cellular senescence via upregulation of p16, p21, and p27

Moreover, a research has shown an inhibitory effect for exosome and microvesicle (EMV), which play a crucial role in tumor metastasis and released by several cancer types including BC (Tomko et al

10.1016/j.biomaterials.2021.121110 71 NolanoA.MedugnoA.TrombettiS.LiccardoR.De RosaM.IzzoP.et al (2023)
