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Microsc Res Tech 59:331334 Li Q, Huang H, He Z, Sun Y, Tang Y, Shang X, Wang C (2018) Regulatory effects of antitumor agent matrine on FOXO and PI3K-AKT pathway in castration-resistant prostate cancer cells

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Jabbour E, Kantarjian HM, Thomas DA, Ravandi F, Cortes JE, Faderl S, Pemmaraju N, Kadia TM, Garris RS, Garcia-Manero G, Borthakur G , Wierda WG, O'Brien SM

Immune cells, such as macrophages and neutrophils, can also generate ROS due to their oxygen-dependent mechanisms to fight against invading microorganisms based on NOX2 isoform ( ROS are produced in mitochondria during aerobic metabolism (Rodriguez and Redman, 2005)