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Description
This comprehensive review critically evaluates recent advances in BBRs anti-obesity pharmacology through three lenses: (1) preclinical and clinical evidence from randomized controlled trials, (2) molecular mechanisms underlying metabolic regulation, and (3) innovative strategies for pharmacokinetic optimization
We primarily hypothesised that kidney oxygenation would be improved in the active treatment groups compared with placebo after 32 weeks
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Primary outcomes included serious adverse events and retained gastric products based on patient records, procedure reports, and procedural videos
