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Clinical trials show meaningful weight reduction in sedentary patients, yet lifestyle changes amplify results and protect long-term success

Sustained Gs signaling mediated by vasopressin type 2 receptors is ligand dependent but endocytosis and -arrestin independent

Margulies KB, Anstrom KJ, Hernandez AF, Redfield MM, Shah MR, Braunwald E, Cappola TP
